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We could then discuss the relation between structure change and hydration of protein, together with other thermodynamic parameters
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As can be seen in Fig
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1 kcal/mol for the first transition and 4
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5 mM PEP at pH 7
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Alternatively, as the size of X
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This is called "wraparound" binding because the two domains in CaM wrap around the α-helical target (8,9)
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The sample was transferred directly from the dialysis bag onto the lower platen, and upper platen lowered until the sample filled the gap (typical gap was 0
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5 there is significant protein dimerization
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Suzanne ScarlataDepartment of Physiology & Biophysics, State University of New York at Stony Brook, New York 11794-8661Submitted November 4, 2004, and accepted for publication January 18, 2005
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Although the exact time of disk reconstitution varies for apA-2 from different pools, our data consistently show that the vesicle-to-disk conversion after heat denaturation of apoA-2:DMPC disks is a slow reaction that takes hours to complete at 24°C
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3 nm high (the average estimation is based on 20 measurements), which otherwise corresponds to the thickness of regular mature insulin amyloid (Khurana et al
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, 2003), the herein-presented data points out that additional temperature-induced destabilization may be a factor broadening the range of accessible fibrillar forms
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The fiber's height at intersegment joints is only 3
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The presence of a quasi-docked conformation potentially complicates the interpretation of FRET data for the hairpin ribozyme
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The samples were subsequently fixed using 1% osmium tetroxide in 0
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An alternate system would automatically switch a drug once it's become an accepted part of the health care system
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RP might therefore save money while avoiding the adverse impacts on patient health associated with patient cost sharing, which typically applies to all drugs (Tamblyn et al
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