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. However, upon unfolding transitions generally distinct shifts of the emission spectra are reported (see for example (4,9-14))
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. Interestingly, the light-scattering melting curves show a smaller heat-induced increase in the particle size for apoA-1 than apoA-2-containing disks (Fig
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. In detail the folding energy landscape will look more like a series of low-dimensional terraces (inset to Fig
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. Thus, the fast unfolding phase is observed in disks and in the mixture of lipid-poor and vesicle-bound apoA-2, whereas the slow unfolding phase is observed in disks only
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