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It was suggested, with the help of some computational studies, that this enhanced stability of the tetramer is mainly due to glycosylation and some stabilizing ionic interactions at the oligomeric interface (18)
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Of particular interest is the question of how preferential interactions in 8 M urea or 6 M GdnCl conspire to make these conditions mimic perfect solvents for proteins
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(42) Similarly, apoptotic cell ingestion in vitro and in vivo increases HGF release from both alveolar macrophages and airway epithelial cells
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078 mN for 275°C, and 2
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6 were affected by an aggregation process which led to poor reproducibility particularly at low NaCl concentration
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Initiation of oligomerization was performed through addition of 100 mM NaCl from a 4 M stock solution to 0
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5%) was added, and the samples were boiled for 5 min before loading the SDS-PAGE gel
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The insulin monomer consists of two chains: a 21-residue-long A-chain and a 30-residue-long B-chain
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Such unspecific effects may contribute to morphological differences in any protein's amyloid samples induced at high temperature
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Fins and meristic features Modes of preanal and postanal myomeres were 14 and 23, respectively
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6, A and B), covering the main area of concentration of P
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The distributional ellipses calculated for summer and fall from the positive stations were small and widely separated
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Each standard concentration was used in triplicate
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The ultimate goal is to have drug companies register their trials from the onset in a government-sponsored database with the results--harms and all--publicly available on a Web site
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88, was much greater than failure to hit errors, M = 0
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