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MSDs above 61°CThe finding that MSDs of native HuBChE tend to be larger than those of soman-inhibited HuBChE starting ~3° below the denaturation temperature of native HuBChE (~64°C) is in line with results from several techniques indicating that denaturation increases atomic flexibility of proteins (17,51,52)
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Hence, this quasi-docked species must also form in the native 4WJ ribozyme, possibly as a precursor to the specifically docked native state (Fig
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