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GR is a 108-kDa, homodimeric flavoenzyme that catalyzes the [beta]-nicotinamide-adenine dinucleotide phosphate (NADPH)-dependent reduction of oxidized glutathione (GSSG) to its reduced form (GSH), thus participating in cellular defense mechanisms against oxidative stress
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Yet the probe sphere always intersects the chain unless it is centered sufficiently far away from the center of mass
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van Dik, and D
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1 shows one of these two possible models
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Physical chemistry of protein solutions
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4 as the correlation between monocations' concentrations necessary for a 50% transition from coil DNA to compact DNA calculated from corresponding compaction curves on Fig
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Although the blank fluorescence for DCVJ is low, DCVJ in the presence of unfolded TTR shows even lower fluorescence than the blank, which could indicate a small quenching effect through binding
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Although the misfolding and aggregation reaction is very complex and of multiple order, all kinetic traces could be fitted to a double exponential function which enabled comparison of kinetic parameters
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The complete reaction can, for simplicity, be divided into four phases, which are schematically depicted in Fig
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This work was supported by the National Institutes of Health GM53132
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Abundance and distributionLarvae Larvae of Argentine sandperch occurred between 36[degrees]42'S and 46[degrees]30'S, mainly in coastal waters, in the vicinity of the 50-m isobath (Fig
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, BiDil's manufacturer, has a monopoly on this patent, which was due to expire in 2007 but has now been extended to 2020 as a result of the drug-maker re-marketing BiDil for use among African Americans
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