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Lightbody holds a B
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Two-dimensional infrared correlation spectroscopy study of the aggregation of cylochrome c in the presence of dimyristoylphosphatidylglycerol
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For comparison, the absolute contact orders of the native-state counterparts are also shown
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Thermodynamics of protein folding: a microscopic view
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The PTS involves a cascade of phosphoryl-transfer steps from phosphoenolpyruvate (PEP) via phosphointermediates of the general cytosolic non-sugar-specific phosphotransferases enzyme I (EI) and the histidine-phosphocarrier (HPr) to sugar-specific enzyme II permeases
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The folding features of both domains are different
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Since the folding process is complex in multidomain proteins, where each domain may be able to refold independently and interdomain interactions may affect the overall folding process, EI can be used, in addition, as a model protein to improve our knowledge of protein folding and assembly of multidomain-oligomeric proteins
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Solution structure of the 40,000 Mr phosphor) 1 transfer complex between the N-terminal domain of enzyme 1 and HPr
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Douglas), University of Colorado at Denver Health Sciences Center; and the Department of Immunology (Dr
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Indeed, administration of high doses of HuBChE confers efficient protection against otherwise lethal doses of nerve agents (24)
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Bonvin** Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands; and [dagger] Laboratory of Physical Chemistry, Swiss Federal Institute of Technology, Zurich, SwitzerlandSubmitted April 23, 2004, and accepted for publication September 20, 2004
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HEUNGSUP PARK AND WALLACE W
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may still be visible
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9 However, in some cases the implant failed and only fibrous tissue was produced
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Table 1: Effect of RP on Days of Analgesic Therapy Dispensed per 1,000Seniors over the Post-RP Period, by Analgesic TypeEstimate p-Value95% CIEffect of Type 1 RPNSAIDsAverage monthly effect-1,293
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([c] 2005 Book News, Inc
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Student-Life Stress Inventory scores were significantly negatively correlated to mental component SF-12 HRQOL scores (p<0
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The reactions to stressors section is comprised of four categories (physiological, emotional, behavioral, and cognitive)
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. Five-hundred milligrams of holomyoglobin (purchased from Sigma, St
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. Although the thermal unfolding of many proteins can successfully be illustrated by a two-state model, step-wise transitions have been observed in several proteins regardless of whether the process was reversible or irreversible (30,38, 39,49-54)
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. To our knowledge, this is the first demonstration of N-glycans affecting protein stability to such a huge extent, except for a report on a fucosylated peptide PMP-C (Pars interecrebralis major peptide C, a 36-residue peptide)
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. Buffer contributions were subtracted, and the resulting spectra were used for analysis
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. The molecular weight of aceturate is 117
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. Circular dichroism (CD) and light-scattering melting curves show hysteresis and scan rate dependence, indicating thermodynamically irreversible transition with high activation energy E^sub a^
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